OPTICULTURE™
SERUM-FREE MEDIUM

Engineered for Reliable, Biocompatible Research

Engineered for Reliable, Biocompatible Research

Nutrient-Rich Serum-Free Composition

Physiological Glucose Levels

Customizable Supplements

Phenol Red–Free

Serum-Free Medium for Advanced Cell-Based Models - Ensuring Reliable, Biocompatible, and Immune-Compatible Cell Cultures

 

OptiCulture™ Serum-Free Medium is a serum-free, phenol red–free, nutrient-rich formulation with physiological glucose levels and customizable supplements. Designed for biocompatible and immune-compatible cultures of cells and organoids, it delivers reproducible, translationally relevant results essential for discovery.

 

One Medium, Many Models:

This medium is particularly suited for Ex vivo cultures of endothelial, epithelial, CNS and retinal cells for:

  • Disease modeling, such as Liver-on-A-Chip, Kidney-on-A-Chip, and Lung-on-A-Chip.
  • Drug screening.
  • Barrier modeling, such as Blood-Brain Barrier (BBB), Blood-Retinal Barrier (BRB).

 

REQUEST A FREE SAMPLE TODAY!

Interested in testing OptiCulture™ in your research? Fill in the formto request a free sample!

Key Features & Benefits:

  • Xeno-Free Kit OptiCulture™ Serum-Free Medium-RH: Formulated without animal-derived components to ensure high reproducibility and bio-/immune-compatibility in sensitive research models.
  • Nutrient-Rich Serum-Free Composition. Provides essential amino acids, lipids, nucleotides, vitamins, and cofactors to sustain healthy, long-lived cultures and support demanding assays.
  • Physiological Glucose Levels. Mirrors in vivo glucose to maintain stable transcriptomic profiles, preserve native cell functions, and reduce experimental artifacts.
  • Phenol Red–Free: Designed for cell culture applications requiring minimal background interference, enabling clearer imaging, precise assay readouts, and reliable hormone-sensitive studies.
  • Recombinant Human Growth Factors or Proprietary Brain-Derived Supplementation. OptiCulture™ kits are available with either recombinant human growth factors (OptiBoom-R) - broadening support across multiple human cell types - or a proprietary brain-derived supplement (OptiBoom-B), tailored for CNS, retinal, and neurovascular models.
  • Customizable Supplements. Separate supplement vials allow researchers to adjust formulations for specific cell types, co-cultures, and experimental conditions - maximizing flexibility and reproducibility.
  • Xeno-Free Kit OptiCulture™ Serum-Free Medium-RH: Formulated without animal-derived components to ensure high reproducibility and bio-/immune-compatibility in sensitive research models.
  • Nutrient-Rich Serum-Free Composition. Provides essential amino acids, lipids, nucleotides, vitamins, and cofactors to sustain healthy, long-lived cultures and support demanding assays.
  • Physiological Glucose Levels. Mirrors in vivo glucose to maintain stable transcriptomic profiles, preserve native cell functions, and reduce experimental artifacts.
  • Phenol Red–Free: Designed for cell culture applications requiring minimal background interference, enabling clearer imaging, precise assay readouts, and reliable hormone-sensitive studies.
  • Recombinant Human Growth Factors or Proprietary Brain-Derived Supplementation. OptiCulture™ kits are available with either recombinant human growth factors (OptiBoom-R) - broadening support across multiple human cell types - or a proprietary brain-derived supplement (OptiBoom-B), tailored for CNS, retinal, and neurovascular models.
  • Customizable Supplements. Separate supplement vials allow researchers to adjust formulations for specific cell types, co-cultures, and experimental conditions - maximizing flexibility and reproducibility.

 

Choose the Set of Supplements that Meet Your Needs

Choose the Set of Supplements that
Meet Your Needs


Our OptiBoom-R™ in OptiCulture™ Serum-Free Medium-RH provides xeno-free and robust supplements, which support the growth and development of normal phenotype of broad spectrum of cells, including endothelial cells and epithelial cells.

Our OptiBoom-R™ in OptiCulture™ Serum-Free Medium-R provides defined and robust supplements, which support the growth and development of normal phenotype of broad spectrum of cells, including endothelial cells and epithelial cells.

Our OptiBoom-B™ in OptiCulture™ Serum-Free Medium-B provides rich and robust nutrients, which support the growth and development of ex vivo phenotype of cells, especially central nervous systems- and retinal-derived endothelial cells, neurons and glial cells.

Request Your Free OptiCulture™ Sample Today!

Interested in OptiCulture™ Medium for your research? Fill out the form below to request a sample, or contact us for more information.


Build your complete, translationally relevant research model today!

Pair the OptiCulture Serum-Free Medium with validated Cell Systems’ Primary Human Cells.