Cell Systems News — Lung Model
Elevating your insights into human cell biology requires a rethinking of each cell model. Presented in 2021, this more predictive and biologically relevant airway epithelial-endothelial model might allow scientists to better understand how our pulmonary system responses to diseases like COVID-19, COPD, asthma, cystic fibrosis and more. For the first time, scientists are co-culturing Calu-3 cells and Primary Human Lung Microvascular Endothelial Cells (from Cell Systems Cat# ACBRI 468) on flexible porous PTMC membranes to build a new airway epithelial-endothelial model that better reflects the lungs’ complexity. Many existing models involve culturing lung epithelial cells on stiff membranes, which is...