A Selection of Citations for 4CB-500 from Scientific Journals
Discover additional research on Google Scholar that utilizes Cell Systems CultureBoost™.

• "Improvement in diabetic retinopathy through protection against retinal apoptosis in spontaneously diabetic Torii rats mediated by ethanol extract of Osteomeles schwerinae C.K. Schneid" Kim, Kim, Kim, et al. Nutrients, 2019.

• "SiRNA silencing of VEGF, IGFs, and their receptors in human retinal microvascular endothelial cells" Nicolau et al American J Translational Research, 2018
• "Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development" Beharry et al. Prostaglandins and Other Lipid Mediators, 2018

• "Tangential flow filtration for highly efficient concentration of extracellular vesicles from large volumes of fluid" Busatto and Vilanilam et al. Cells, 2018.

• "Barrier properties and transcriptome expression in human iPSC‐derived models of the blood–brain barrier" Delsing et al. Stem Cells, 2018.

• "MnTBAP or catalase Is more protective against oxidative stress in human retinal endothelial cells exposed to Intermittent hypoxia than their co-administration" Quan et al. Reactive Oxygen Species, 2017

• "Association of HMGB1 with oxidative stress markers and regulators in PDR" Abu El-Asrar and Alam et al. Molecular Vision, 2017.

• "Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells" Wang et al. Journal of Cell Science, 2016.

• "Fenofibrate Inhibits cytochrome P450 epoxygenase 2C activity to suppress pathological ocular angiogenesis" Gong et al. EBioMedicine, 2016.

• "Primary human liver co-culture With flow and Kupffer cell integration on microfluidic liver-on-a-chip" Mazur  (Dissertation thesis), 2015.

• "Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines" Momeny et al. Oncotarget, 2015.

• "Aflibercept traps galectin-1, an angiogenic factor associated with diabetic retinopathy"  Kanda et al.  Scientific Reports, 2015.

• "Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells"  Liu et al. PLoS One, 2014.

• "S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis" Abu El-Asrar et al. Molecular Vision, 2014.

• "Differential expression and role of hyperglycemia induced oxidative stress in epigenetic regulation of β1, β2 and β3-adrenergic receptors in retinal endothelial cells" Safi et al. BMC Medical Genomics, 2014.

• "Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells" Sullivan et al. Molecular Pharmacology, 2012.

• "High-glucose-induced endothelial cell injury is inhibited by a peptide derived from human Apolipoprotein E"  Bhattacharjee et al. PLoS One, 2012.

CultureBoost™ has two main uses.

1. Application as a growth supplement to medium:

Cell Systems Complete Medium Kit (4Z0-500) and Cell Systems Medium Minus Serum Kit (4Z3-500) each include a 5mL vial of CultureBoost-R™ (4CB-500-R).

CultureBoost™ can be purchased separately (4CB-500) to supplement Cell Systems Media Kit without Growth Factor (4Z0-500-S) or other cell culture media.

2. Application in the vial thaw procedure:

Cells are at their most fragile when in recovery from thawing or passage. The growth factors in CultureBoost™ and CultureBoost-R™ stabilize the plasma membrane and provide a concentrated dose of factors that have been shown to aid the cell in attachment, activation, and achievement of polarity.

CultureBoost™ can be beneficially used any time cells are "loosened" from the pellet prior to resuspension in Cell Systems Medium in preparation for plating. The best results of using CultureBoost™ are evident when 50-100 microliters are added to the loosened cell pellet just prior to re-suspension in medium. Please refer to the instructions for our Passage Reagent Group™ (4Z0-800).